TRENDS OF GALLSTONE DISEASE INCIDENCE IN KAZAKHSTAN
NS IGISSINOV1,2,3,4, https://orcid.org/0000-0002-2517-6315,
SK KOZHAKHMETOV1,3, https://orcid.org/0000-0002-0075-0376,
DT TUREBAYEV1, https://orcid.org/0000-0003-1557-3496,
KT ADAIBAYEV1, https://orcid.org/0000-0002-9145-1661,
NA BIKHANOV5, https://orcid.org/0000-0002-0890-4763,
ZA BILYALOVA3, https://orcid.org/0000-0002-0066-235X
1Astana Medical University, Nur-Sultan с., Republic of Kazakhstan,
2International School of Medicine, Bishkek с., Republic of Kyrgyzstan,
3Central Asian Cancer Institute, Nur-Sultan с., Republic of Kazakhstan,
4Eurasian Institute for Cancer Research, Bishkek с., Republic of Kyrgyzstan,
5City Hospital № 1, Nur-Sultan с., Republic of Kazakhstan
identify the risk factors in population, epidemiological studies have to first determine the frequency of the disease.
Objective. To study trends of gallstone disease incidence in Kazakhstan.
Material and methods. The material of the study was the data of the consolidated reporting form No. 12 of the Ministry of Healthcare of the Republic of Kazakhstan on new cases of gallstone disease (ICD: K00-K99). We used data on the number of the studied population groups from the Statistical Committee of the Ministry of National Economy of the Republic of Kazakhstan. The study is retrospective for the period of 2006-2015. According to conventional methods of biomedical statistics, extensive, intensive and aligned incidence rates of Gallstone disease were calculated.
Results. The average annual incidence of gallstone disease among the entire population of Kazakhstan was 70.7±3.20/0000 (95% CI=64.4-77.0), and among the studied population groups it was: among children – 10.9±1.70/0000 (95% CI=7.5-14.2), among adolescents – 30.6±2,30/0000 (95% CI=26.1-35.2) and among adults population – 94.8±4.90/0000 (95% CI=85.1-104.4). Differences in incidence between groups were statistically significant. The trends in incidence rate had tendency of increase among the adult population (Tin=+4.6%), and tendency of decrease among children (Tdec=−9.4%) and adolescents (Tdec=−5.1%).
Conclusion. In dynamics, the incidence of bile stone disease in Kazakhstan as a whole tends to increase due to the adult population. The results are recommended to take into account the health organisations when making management decisions.
Keywords: gallstone disease, incidence, trends, Kazakhstan.