УДК 616.858-036.22-077
A.A. Akanova^1,2, A.K. Yeshmanova², K.K. Akanova¹, S.U. Kamenova¹,
A.G. Beltenova^1,2, K.B. Raimkulova^1
1Kazakh National Medical University named after S.D. Asfendiayrov, Virtual Institute of Neurosciences, Almaty c.,
²The innovative school of Gerontology and Geriatrics, Almaty c

EVALUATION OF NON-MOTOR SYMPTOMS AND COGNITIVE CHANGES IN PARKINSON DISEASE

Parkinson Disease is a progressive neurodegenerative disease that has motor symptoms such as bradykinesia, tremor, muscle rigidity and postural instability. The non-motor symptoms include depression, anxiety, cognitive status changes and dementia at the very advanced stages. There is very little research on PD in Kazakhstan, therefore, this study aimed to assess some of non-motror symptoms in PD patients in Almaty. The assesment of the FAB, MMSE and Clock-drawing scale showed that there was a significant impairment in the cognitive status of the PD patients compared to the control age-matched subjects (n control=39, n PD =39; Anova, p=0,001). The Schwab-England scale for the assessment of activity of the daily living, Spielberg Trait Anxiety Test and Visual Analogue Scale EuroQoL-5D showed that there higher frequency of highly stressed and disabled people in the PD group compared to the age-matched control group.
Key words: Parkinson Disease, neuropsychiatric clinical scales, cognition, anxiety, pain.

 

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