ETHNIC GROUPS AND COLORECTAL CANCER. A RETROSPECTIVE STUDY IN KAZAKHSTAN
Rasim A. KERIMOV, http://orcid.org/0000-0001-6156-0958,
Murat E. ZHANTEYEV, http://orcid.org/0000-0002-5387-3476,
Saule B. BISSIMBAYEVA, https://orcid.org/0000-0002-2234-3368
South Kazakhstan Medical Academy, Shymkent, Republic of Kazakhstan
In 2018 compared to 2010, the incidence rate of colorectal cancer increased by 1.8 folds. In this regard, studies aimed at studying the risk factors of this disease have been actualized. In many publications, it was shown that different ethnic groups had unequal risks for colorectal cancer development.
The purpose of this study was to investigate the link between ethnic groups and colorectal cancer in Kazakhstan.
Material and methods. Patients’ medical records, which were made from 2011 to 2016, were studied in 4 regional oncology centres. The group of patients with colorectal cancer and the group of patients with no malignant diseases were compared. There were 1570 cases in each group. Based on the results of the data obtained, such indicators as the chi-square test and relative risks were calculated.
Results and discussion. The analysis showed that in the patient group the share of Russians was higher than that in the control group and in the population. The strength of the association was estimated as moderate (χ2(2)=487.3, p<0.001). This association may be caused by many factors what requires additional research.
1. The analysis showed that different ethnic groups had unequal risks for colorectal cancer development;
2. Such a difference might be due to the nature of the diet, susceptibility of the ethnic group to the disease, the level of seeking of the medical assistance, involvement in a healthy lifestyle;
3. More research is needed to clarify the association.
Keywords: colorectal cancer, cancer of the colon and rectum, ethnic groups, Kazakhstan.